News

Carcinoma mammario: Seagen annuncia i risultati a lungo termine dello studio registrativo di tucatinib

Seagen Inc. ha annunciato oggi che i miglioramenti nella sopravvivenza globale (Overall Survival, OS) e nella sopravvivenza libera da progressione (Progression-Free Survival, PFS) sono stati mantenuti con un follow-up a lungo termine dello studio registrativo HER2CLIMB, che ha valutato l’aggiunta di  tucatinib a trastuzumab e capecitabina in pazienti con carcinoma mammario metastatico HER2-positivo con e senza metastasi cerebrali. I dati dell’analisi esplorativa prespecificata (Abstract n. 1043) saranno presentati nell’ambito del programma scientifico virtuale della conferenza annuale della Società Americana di Oncologia Clinica (ASCO) 2021.

Il beneficio in termini di sopravvivenza globale osservato con tucatinib al momento dell’analisi primaria è stato mantenuto dopo 15,6 mesi aggiuntivi di follow-up (totale di 29,6 mesi), dimostrando un miglioramento di 5,5 mesi nella OS mediana (24,7 mesi (intervallo di confidenza [IC] al 95%: 21,6, 28,9) per il regime con tucatinib rispetto a 19,2 mesi (IC al 95%: 16,4, 21,4) per capecitabina e trastuzumab da soli). Questo beneficio ha continuato a essere generalmente consistente nei sottogruppi di pazienti prespecificati.

“Il carcinoma metastatico HER2-positivo in stadio avanzato si è dimostrato difficile da trattare”, ha affermato il Prof. Giuseppe Curigliano, responsabile della Divisione Sviluppo Nuovi Farmaci presso l’Istituto Europeo di Oncologia, IRCCS, e professore associato di oncologia medica, Università di Milano. “Questi dati supportano ulteriormente il fatto che il trattamento con il regime con tucatinib aiuta i pazienti a vivere più a lungo rispetto a trastuzumab e capecitabina da soli. Questi benefici sono stati osservati in tutti i sottogruppi prespecificati di pazienti nella sperimentazione, inclusi quelli con o senza metastasi cerebrali.”

“Questi risultati supportano l’impatto significativo che un regime con tucatinib può avere sui pazienti con carcinoma mammario metastatico HER2-positivo”, ha affermato il Dott. Roger D. Dansey, responsabile medico di Seagen. “I dati a lungo termine dello studio HER2CLIMB hanno dimostrato che il beneficio in termini di sopravvivenza è stato sostenuto con la sopravvivenza globale mediana più prolungata rispetto a quella osservata nell’analisi primaria.”

Video

Uniquely strategize progressive markets rather than frictionless manufactured products. Collaboratively engineer reliable.

Advertisement

Advertisement Small

Flickr

  • Coral Way (trolley)
  • Trolley
  • Coral Gables
  • The Alhambra Water Tower
  • Janne
  • Calots
  • Wishful thinking
  • Yes, I am ...
  • End of a way

About Author

Follow Me

Collaboratively harness market-driven processes whereas resource-leveling internal or "organic" sources. Competently formulate.

ThemeForest

Collaboratively harness market-driven processes whereas resource-leveling internal or "organic" sources. Competently formulate.

Calendar

Settembre 2023
L M M G V S D
 123
45678910
11121314151617
18192021222324
252627282930  

RSS Meks Blog

  • 10 Best Knowledge Base & Wiki WordPress Themes 2021 15 Settembre 2021
    Running a successful online business requires an exceptional WordPress knowledge base theme that organizes documentation and helps customers. Customization options, intuitive navigation, unique layouts, and fast responsiveness are just some of the features you need. The following 10 WordPress wiki themes represent the best options for 2021 and beyond. Explore the full range to determine […]
    Dusan Milovanovic
  • How to increase WordPress Memory Limit (quick fixes) 16 Giugno 2021
    Here is a post about how to increase the memory limit in WordPress. Allowed memory size exhausted error message showed up in your WordPress installation? No worries – this is one of the most common errors in WordPress. You can apply an easy fix by increasing the memory limit in your PHP. Table of Contents […]
    Dusan Milovanovic
  • How to use (and why) WordPress sitemap plugin 1 Marzo 2021
    Did you know that by knowing how to use the WordPress sitemap plugin you can significantly improve your site’s visibility and traffic? Although it isn’t mandatory to have a sitemap on your site, having one significantly improves the site’s quality, crawlability and indexing. All this is important for better optimization, which is why we wanted […]
    Ivana Cirkovic
  • 22 free and premium podcast software for your show [2021 edition] 18 Gennaio 2021
    You’re determined to start or improve your podcast but don’t know which podcast software to use to really make it stand out? We’ve got you! #podcasting Top 22 free and premium podcast software for your show #WordPressTips #podcasting The post 22 free and premium podcast software for your show [2021 edition] appeared first on Meks.
    Ivana Cirkovic
  • Digital storytelling with WordPress – an all-in-one guide to make your web stories pop! 23 Novembre 2020
    Wondering how to improve digital storytelling with WordPress and build more awareness and exposure of your business? Let our guide lead the way. The post Digital storytelling with WordPress – an all-in-one guide to make your web stories pop! appeared first on Meks.
    Ivana Cirkovic
  • How to use WordPress autoposting plugin to improve your visibility and SEO? 10 Settembre 2020
    Did you know you can use the WordPress autoposting plugin for your content efforts and improve not only your time management but your business and visibility as well? The post How to use WordPress autoposting plugin to improve your visibility and SEO? appeared first on Meks.
    Ivana Cirkovic
  • How to create a personal branding site? Step-by-step DIY guide 15 Agosto 2020
    Looking for ways and means to create a personal branding site? Well, look no further ’cause we’re giving away all the how-to’s to do it yourselves! The post How to create a personal branding site? Step-by-step DIY guide appeared first on Meks.
    Ivana Cirkovic
  • Top 15 WordPress content plugins and tools to improve your visibility and rankings 16 Luglio 2020
    Let’s take a look at some of the must-have WordPress content plugins and tools to use to improve both your UX and rankings. The post Top 15 WordPress content plugins and tools to improve your visibility and rankings appeared first on Meks.
    Ivana Cirkovic
  • WCEU 2020 recap – key takeaways from the biggest online WordPress conference 9 Giugno 2020
    Missed WCEU 2020 and all the exciting stuff from there? Here are all the key takeaways and main points to remember so, take notes! The post WCEU 2020 recap – key takeaways from the biggest online WordPress conference appeared first on Meks.
    Ivana Cirkovic
  • How to change the WordPress username? An easy step-by-step guide 14 Maggio 2020
    Wondering how can you change WordPress username once you set up your blog or site? Read all about it in our helpful guide! The post How to change the WordPress username? An easy step-by-step guide appeared first on Meks.
    Ivana Cirkovic

Text

Distinctively utilize long-term high-impact total linkage whereas high-payoff experiences. Appropriately communicate 24/365.